17. Peyton Manning | Indianapolis Colts, 1998 | passer rating: 71.2In 1998, his rookie season, Peyton Manning threw 26 touchdowns but led the NFL with 28 interceptions. That could be partly because he also led the league in passing attempts, completing 56.7 percent of his 575 attempts. Manning finished that first season of his Hall of Fame-worthy career with a 71.2 passer rating.(Jamie Squire / Getty Images)